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Mortality and Acute Kidney Injury in Asians With Atrial Fibrillation Treated With Dabigatran or Warfarin
Ist Teil von
Journal of the American College of Cardiology, 2017-05, Vol.69 (19), p.2471-2471
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
2017
Quelle
Free E-Journal (出版社公開部分のみ)
Beschreibungen/Notizen
We read with interest the recently published study by Chan et al. (1). The authors reported that dabigatran was associated with a surprisingly low risk of acute kidney injury and mortality compared with warfarin in a large Asian cohort either with or without a history of chronic kidney disease (CKD). However, especially the reported differences in mortality (after on average 0.7 years) is rather implausible and is inconsistent with findings from randomized clinical trials, such as the RE-LY study (2)or its subgroup analysis based on patients from Asian countries (3) and a recent meta-analysis (4).