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Magnesium Status and Its Association with Oxidative Stress in Obese Women
Ist Teil von
Biological trace element research, 2017-02, Vol.175 (2), p.306-311
Ort / Verlag
New York: Springer US
Erscheinungsjahr
2017
Quelle
MEDLINE
Beschreibungen/Notizen
The aim of this study was to assess the relationship between magnesium status and oxidative stress in obese and nonobese women. This cross-sectional study included 83 women, aged between 20 and 50 years, who were divided into two groups: the obese group (
n
= 31) and the control group (
n
= 52). The control group was age-matched with the obese group. Magnesium intake was monitored using 3-day food records and NutWin software version 1.5. The plasma and erythrocyte magnesium concentrations were determined by flame atomic absorption spectrophotometry. Plasma levels of thiobarbituric acid reactive substances (TBARS) were determined as biomarkers for lipid peroxidation and therefore of oxidative stress. The mean values of the magnesium content in the diet were found to be lower than those recommended, though there was no significant difference between groups (
p
> 0.05). The mean concentrations of plasma and erythrocyte magnesium were within the normal range, with no significant difference between groups (
p
> 0.05). The mean concentration of plasma TBARS was higher in obese woman, and the difference between the groups was statistically different (
p
< 0.05). There was a positive correlation between erythrocyte magnesium and plasma TBARS in the obese group (
p
= 0.021). Obese patients ingest low dietary magnesium content, which does not seem to affect the plasma and erythrocyte concentrations of the mineral. The study showed a negative correlation between erythrocyte magnesium concentrations and plasma TBARS, suggesting the influence of magnesium status on the parameters of oxidative stress in obese women.