Infection, genetics and evolution, 2017-09, Vol.53, p.56-67
2017
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- Autor(en) / Beteiligte
- Titel
- Genetic and phylogenetic characterizations of a novel genotype of highly pathogenic avian influenza (HPAI) H5N8 viruses in 2016/2017 in South Korea
- Ist Teil von
- Infection, genetics and evolution, 2017-09, Vol.53, p.56-67
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 2017
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- During the outbreaks of highly pathogenic avian influenza (HPAI) H5N6 viruses in 2016 in South Korea, novel H5N8 viruses were also isolated from migratory birds. Phylogenetic analysis revealed that the HA gene of these H5N8 viruses belonged to clade 2.3.4.4, similarly to recent H5Nx viruses, and originated from A/Brk/Korea/Gochang1/14(H5N8), a minor lineage of H5N8 that appeared in 2014 and then disappeared. At least four reassortment events occurred with different subtypes (H5N8, H7N7, H3N8 and H10N7) and a chicken challenge study revealed that they were classified as HPAI viruses according to OIE criteria. •Novel H5N8 isolates isolated from migratory birds in South Korea, 2016/17 winter.•The H5N8 virus was the reassortants generated from at least four different subtypes.•Chicken study revealed that they were classified as HPAI according to OIE criteria.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1567-1348eISSN: 1567-7257DOI: 10.1016/j.meegid.2017.05.001Titel-ID: cdi_proquest_miscellaneous_1896415936
- Format
- –
- Schlagworte
- Animals, Animals, Wild, Birds - virology, Chickens, Disease Outbreaks - veterinary, Genotype, Hemagglutinin Glycoproteins, Influenza Virus - genetics, HPAI H5N6 virus, HPAI H5N8 virus, Influenza A Virus, H10N7 Subtype - classification, Influenza A Virus, H10N7 Subtype - genetics, Influenza A Virus, H10N7 Subtype - isolation & purification, Influenza A Virus, H3N8 Subtype - classification, Influenza A Virus, H3N8 Subtype - genetics, Influenza A Virus, H3N8 Subtype - isolation & purification, Influenza A Virus, H5N8 Subtype - classification, Influenza A Virus, H5N8 Subtype - genetics, Influenza A Virus, H5N8 Subtype - isolation & purification, Influenza A Virus, H7N7 Subtype - classification, Influenza A Virus, H7N7 Subtype - genetics, Influenza A Virus, H7N7 Subtype - isolation & purification, Influenza in Birds - epidemiology, Influenza in Birds - virology, Migratory birds, Phylogeny, Phylogeography, Reassortant, Reassortant Viruses - classification, Reassortant Viruses - genetics, Reassortant Viruses - isolation & purification, Republic of Korea - epidemiology, South Korea