Details

Autor(en) / Beteiligte

• Zalesskiy, Sergey S
• Shlapakov, Nikita S
• Ananikov, Valentine P

Titel

Visible light mediated metal-free thiol-yne click reaction

Ist Teil von

• Chemical science (Cambridge), 2016-01, Vol.7 (11), p.6740-6745

Ort / Verlag

England

Erscheinungsjahr

2016

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• The carbon-sulfur bond formation reaction is of paramount importance for functionalized materials design, as well as for biochemical applications. The use of expensive metal-based catalysts and the consequent contamination with trace metal impurities are challenging drawbacks of the existing methodologies. Here, we describe the first environmentally friendly metal-free photoredox pathway to the thiol-yne click reaction. Using Eosin Y as a cheap and readily available catalyst, C-S coupling products were obtained in high yields (up to 91%) and excellent selectivity (up to 60 : 1). A 3D-printed photoreactor was developed to create arrays of parallel reactions with temperature stabilization to improve the performance of the catalytic system.