Details

Autor(en) / Beteiligte

• Jin, Jing-Hai
• Li, Xiang-Yu
• Luo, Xiaoyan
• Fossey, John S
• Deng, Wei-Ping

Titel

Asymmetric Synthesis of cis-3,4-Dihydrocoumarins via [4 + 2] Cycloadditions Catalyzed by Amidine Derivatives

Ist Teil von

• Journal of organic chemistry, 2017-05, Vol.82 (10), p.5424-5432

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A highly efficient chiral amidine derivative-catalyzed tandem Michael addition/lactonization of carboxylic acids and o-quinone methides (o-QMs) has been developed that enables the asymmetric synthesis of cis-3,4-dihydrocoumarins bearing contiguous tertiary stereogenic centers in high yields with excellent stereoselectivities.