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Association between body size, weight change and depression: systematic review and meta-analysis
Ist Teil von
British journal of psychiatry, 2017-07, Vol.211 (1), p.14-21
Ort / Verlag
Cambridge, UK: Cambridge University Press
Erscheinungsjahr
2017
Link zum Volltext
Quelle
Applied Social Sciences Index & Abstracts (ASSIA)
Beschreibungen/Notizen
The association between body size, weight change and depression has not been systematically summarised, especially for individuals who are underweight.
To conduct a systematic review and a meta-analysis to examine the association between indices of body size, weight change and depression.
A total of 183 studies were selected. Fully adjusted hazard ratios (HRs) or odds ratios (ORs) were extracted. A total of 76 studies contributed to data synthesis with a random-effect model, and subgroup analyses were conducted to evaluate the effect of potential moderators.
In cohort studies, underweight at baseline increased the risk of subsequent depression (OR = 1.16, 95% CI 1.08-1.24). Overweight (BMI 25-29.9 kg/m
) showed no statistically significant relationship with depression overall; however, the subgroup analyses found different results according to gender (men: OR = 0.84, 95% CI 0.72-0.97, women: OR = 1.16, 95% CI 1.07-1.25). In cross-sectional designs, obesity with BMI >40 kg/m
showed a greater pooled odds ratio than obesity with BMI >30 kg/m
Both underweight and obesity increase the risk of depression. The association between overweight and depression differs by gender.