Details

Autor(en) / Beteiligte

• Flick, Andrew C
• Ding, Hong X
• Leverett, Carolyn A
• Kyne, Robert E
• Liu, Kevin K. -C
• Fink, Sarah J
• O’Donnell, Christopher J

Titel

Synthetic Approaches to the New Drugs Approved During 2015

Ist Teil von

• Journal of medicinal chemistry, 2017-08, Vol.60 (15), p.6480-6515

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 29 new chemical entities (NCEs) that were approved for the first time in 2015.