UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 5 von 53
Datensatz exportieren als...
BibTeX
Utility of a routine medical surveillance program with benzene exposed workers
American journal of industrial medicine, 2003-11, Vol.44 (5), p.467-473
Bogadi-Šare, Ana
Zavalić, Marija
Turk, Rajka
2003
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Bogadi-Šare, Ana
Zavalić, Marija
Turk, Rajka
Titel
Utility of a routine medical surveillance program with benzene exposed workers
Ist Teil von
American journal of industrial medicine, 2003-11, Vol.44 (5), p.467-473
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2003
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
Background A medical surveillance program of benzene‐exposed workers has to be established in such a way as to observe early signs of benzene‐induced cytopenia, pancytopenia, or leukemia. This study evaluates the utility of routine medical survey applied to benzene‐exposed workers by analyzing the hematological, immunological, and cytogenetic assay results. Methods The results of a previous study of hematological, immunological, and cytogenetic assays in benzene‐exposed workers (up to 15 ppm) are used to discuss medical surveillance program by defining the relationship between various benzene exposure concentrations and toxic endpoints. Results Exposure to benzene concentration lower than 5 ppm does not produce any abnormal hematological measurements. For benzene cumulative exposure above 100 (ppm‐years), some blood indices [mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), band neutrophils] show significant differences in comparison to the control group. The incidence of dicentric chromosomes was higher and the level of B‐lymphocytes was lower even with workers exposed to 5 ppm of benzene; correlation with exposure indicators was not found. Conclusions The results suggest that peripheral blood indices, although not sensitive enough, are still the most suitable parameters in a health surveillance program applied to benzene‐exposed workers. B‐lymphocytes could be a promising indicator of the benzene‐induced damage. Cytogenetic tests did not prove to be suitable. Further investigation of useful screening tests for health surveillance program of benzene‐exposed workers is still required. Am. J. Ind. Med. 44:467–473, 2003. © 2003 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 0271-3586
eISSN: 1097-0274
DOI: 10.1002/ajim.10296
Titel-ID: cdi_proquest_miscellaneous_18888232
Format
–
Schlagworte
Adult
,
benzene
,
Benzene - adverse effects
,
Biological and medical sciences
,
Chemical and industrial products toxicology. Toxic occupational diseases
,
Female
,
genotoxicity
,
Hematologic Diseases - diagnosis
,
Hematologic Diseases - etiology
,
hematotoxicity
,
Humans
,
immunotoxicity
,
Industry
,
Mass Screening - methods
,
Medical sciences
,
medical surveillance program
,
Middle Aged
,
Occupational Diseases - diagnosis
,
Occupational Diseases - etiology
,
Occupational Health
,
Population Surveillance - methods
,
Shoes
,
Toxicology
,
Various organic compounds
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX