Journal of hepatology, 2017-08, Vol.67 (2), p.415-417
2017
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- Autor(en) / Beteiligte
- Titel
- Occurrence of hepatocellular carcinoma in HIV/HCV co-infected patients treated with direct-acting antivirals
- Ist Teil von
- Journal of hepatology, 2017-08, Vol.67 (2), p.415-417
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 2017
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Abstract Controversial data on high incidence of hepatocellular carcinoma (HCC) in patients with HCV-related liver disease treated with interferon-free anti-HCV direct-acting antivirals has been reported Even higher risk of de novo HCC has been envisaged in the subpopulation of HIV/HCV co-infected patients in whom cancer immune-surveillance might be decreased. We present 118 consecutive HIV/HCV co-infected patients undergoing DAAs-based treatment, in which the observed de novo HCC incidence was 2.5% after a median follow-up of 85 weeks, therefore non-significantly increased compared to HIV-negative subjects.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0168-8278eISSN: 1600-0641DOI: 10.1016/j.jhep.2017.03.032Titel-ID: cdi_proquest_miscellaneous_1888680942
- Format
- –
- Schlagworte
- Antiviral agents, Antiviral Agents - adverse effects, Antiviral Agents - therapeutic use, Carcinoma, Hepatocellular - chemically induced, Carcinoma, Hepatocellular - etiology, Carcinoma, Hepatocellular - virology, Coinfection - drug therapy, Coinfection - etiology, Coinfection - virology, Female, Gastroenterology and Hepatology, Hepatitis C - complications, Hepatitis C - drug therapy, Hepatocellular carcinoma, HIV Infections - complications, HIV Infections - drug therapy, Humans, Liver Neoplasms - chemically induced, Liver Neoplasms - etiology, Liver Neoplasms - virology, Male, Middle Aged