Details

Autor(en) / Beteiligte

• Mu, Delong
• Wang, Xinmou
• Chen, Gong
• He, Gang

Titel

Iridium-Catalyzed ortho-C(sp2)–H Amidation of Benzaldehydes with Organic Azides

Ist Teil von

• Journal of organic chemistry, 2017-04, Vol.82 (8), p.4497-4503

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An iridium-catalyzed ortho-C­(sp2)–H amidation reaction of benzaldehydes with organic azides has been developed. A catalytic amount of 3,5-di­(trifluoromethyl)­aniline was used to promote the Ir-catalyzed directed C–H amination reaction through a transient aldimine intermediate. This reaction tolerates a broad scope of benzaldehyde substrates and works well with a range of aryl- and alkylsulfonyl azides.