Details

Autor(en) / Beteiligte

• Yang, Xinglin
• Shan, Gang
• Yang, Zimo
• Huang, Guiyi
• Dong, Guoqiang
• Sheng, Chunquan
• Rao, Yu

Titel

One-pot synthesis of quaternary carbon centered cyclobutanes via Pd(ii)-catalyzed cascade C(sp 3 )-H activations

Ist Teil von

• Chemical communications (Cambridge, England), 2017, Vol.53 (9), p.1534-1537

Ort / Verlag

England

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A novel approach toward quaternary carbon centered cyclobutanes through Pd(ii)-catalyzed sequential intramolecular methylene C-H alkylation and intermolecular methine C-H bond arylation, alkenylation, alkylation, alkynylation, allylation, benzylation or alkoxylation is described. These quaternary carbon centered cyclobutanes could be further diversified through Pd(ii)-catalyzed γ-C(sp )-H bond activations. The synthetic utility of this novel approach was exemplified by its application to the synthesis of a bioactive small molecule.