Details

Autor(en) / Beteiligte

• Chen, Jingwen
• Zhang, Zhiguo
• Bao, Zongbi
• Su, Ye
• Xing, Huabin
• Yang, Qiwei
• Ren, Qilong

Titel

Functionalized Metal–Organic Framework as a Biomimetic Heterogeneous Catalyst for Transfer Hydrogenation of Imines

Ist Teil von

• ACS applied materials & interfaces, 2017-03, Vol.9 (11), p.9772-9777

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Mimicking a biocatalytic system has been one of the prevalent strategies for the design of novel and efficient chemical transformations. Among the enzyme-catalyzed reactions, the cooperative interplay of Lewis- and Brønsted-acidic functionalities at active sites represents a common feature in activating reactants. Employing MIL-101­(Cr) as a biomimetic platform, we customize a sulfonic group (SO3H) into its hierarchical pores to generate a heterogeneous catalyst for transfer hydrogenation of imines by using Hantzsch ester as the reductant. Both aldimines and ketimines were efficiently converted to their hydrogenated counterparts in a manner similar to metal enzymes. The Cr3+ node and sulfonic acid functionality encapsulated in MOF cages worked cooperatively in promoting this transformation, resulting in an enhanced reactivity as compared to its homogeneous analogue. Furthermore, MIL-101­(Cr)-SO3H could be recycled for many times without considerable loss in reactivity.