Environmental toxicology and pharmacology, 2016-12, Vol.48, p.286-293
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Study on the relationship of genotoxic and oxidative potential of a new mixed chelate copper antitumoral drug, Casiopeina II-gly (Cas II-gly) in Drosophila melanogaster
- Ist Teil von
- Environmental toxicology and pharmacology, 2016-12, Vol.48, p.286-293
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 2016
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Highlights • Casiopeina II gly is an antineoplastic coordination compound designed in México • Gentotoxicity of Cas II-gly was evaluated in somatic cells of Drosophila. • Sod and Cat activities and lipid peroxidation were measured. • Enzyme activity and genotoxic damage increasead in a dose response relationship • Relationship between oxidative stress and genetic damage induced by Cas II-gly was found
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1382-6689eISSN: 1872-7077DOI: 10.1016/j.etap.2016.11.008Titel-ID: cdi_proquest_miscellaneous_1868337091
- Format
- –
- Schlagworte
- Animals, Antineoplastic Agents - toxicity, Catalase, Catalase - metabolism, Chelates, Chelating Agents - toxicity, Chromosome aberrations, Copper - metabolism, Dose-Response Relationship, Drug, Drosophila melanogaster, Drosophila melanogaster - drug effects, Drosophila melanogaster - genetics, Drosophila melanogaster - metabolism, Emergency, Enzymes, Exposure, Female, Genotoxicity, Larvae, Lethal Dose 50, Lipid Peroxidation - drug effects, Lipid Peroxidation - genetics, Male, Medical treatment, Mutagens - toxicity, Mutation, Organometallic Compounds - toxicity, Oxidative Stress - drug effects, Oxidative Stress - genetics, Recombination, Recombination, Genetic - drug effects, Studies, Superoxide dismutase, Superoxide Dismutase - metabolism, Toxicity, Wings, Animal - drug effects