Details

Autor(en) / Beteiligte

• Tesche, Christian, MD
• De Cecco, Carlo N., MD, PhD
• Vliegenthart, Rozemarijn, MD, PhD
• Albrecht, Moritz H., MD
• Varga-Szemes, Akos, MD, PhD
• Duguay, Taylor M., BS
• Ebersberger, Ullrich, MD
• Bayer, Richard R., MD
• Canstein, Christian, MSc
• Schmidt, Bernhard, PhD
• Allmendinger, Thomas, PhD
• Litwin, Sheldon E., MD
• Morris, Pamela B., MD
• Flohr, Thomas G., PhD
• Hoffmann, Ellen, MD
• Schoepf, U. Joseph, MD

Titel

Accuracy and Radiation Dose Reduction using Low Voltage Computed Tomography Coronary Artery Calcium Scoring with Tin Filtration

Ist Teil von

• The American journal of cardiology, 2017-02, Vol.119 (4), p.675-680

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract This study prospectively investigated the accuracy and radiation dose reduction of CT coronary artery calcium scoring (CACS) using a 100kVp acquisition protocol with tin filtration (Sn100kVp) compared to the standard 120kVp acquisition protocol. 70 patients (59% male, 62.1±10.7 years) who underwent a clinically-indicated CACS acquisition using the standard 120kVp protocol on a 3rd generation dual-source CT (DSCT) system were enrolled. An additional Sn100kVp CACS scan was performed. Agatston scores and categories, percentile-based risk categorization, and radiation dose estimates were derived from 120kVp and Sn100kVp studies and compared. Median Agatston scores from the Sn100kVp and 120kVp acquisitions were 38.2 and 41.2, respectively ( p <0.0001). Excellent correlation of Agatston scores was found between the two acquisitions ( r =0.99, p <0.0001). Even though the Agatston scores were systematically lower with Sn100kVp than with 120kVp, the comparison of Agatston score categories and percentile-based cardiac risk categories showed excellent agreement (ĸ=0.98 and ĸ=0.98). Image noise was 26.3±5.7HU in Sn100kVp and 17.6±4.1HU in 120kVP scans ( p <0.0001). The dose-length-product was 14.1±3.7mGy*cm with Sn100kVp and 58.5±23.5mGy*cm with 120kVp scans ( p <0.0001), resulting in a significantly lower effective radiation dose (0.19±0.05mSv vs. 0.82±0.32mSv, p <0.0001) for Sn100kVp scans. CACS using a low voltage tin filtration protocol shows excellent correlation and agreement with the standard method with regards to the Agatston score and subsequent cardiac risk categorization, while achieving a 75% reduction in radiation dose.