Doklady. Biochemistry and biophysics, 2016-11, Vol.471 (1), p.410-412
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Enzymatic antioxidant system of endotheliocytes
- Ist Teil von
- Doklady. Biochemistry and biophysics, 2016-11, Vol.471 (1), p.410-412
- Ort / Verlag
- Moscow: Pleiades Publishing
- Erscheinungsjahr
- 2016
- Quelle
- SpringerLink
- Beschreibungen/Notizen
- It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the “classic” antioxidant enzymes (Cu,Zn-superoxide dismutase, catalase, and Se-containing glutathione peroxidase). At the same time, a high expression level of peroxiredoxin genes was identified in the same endothelial cells, which obviously indicates the predominant involvement of these enzymes in protecting the endothelium from the damaging effect of free radical peroxidation.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1607-6729eISSN: 1608-3091DOI: 10.1134/S1607672916060090Titel-ID: cdi_proquest_miscellaneous_1868322108
- Format
- –
- Schlagworte
- Antioxidants, Biochemistry, Biological and Medical Physics, Biomedical and Life Sciences, Biophysics, Catalase - metabolism, Cells, Cultured, Endothelial Cells - enzymology, Enzymes, Erythrocytes - enzymology, Gene Expression, Glutathione Peroxidase - metabolism, Humans, Life Sciences, Molecular Biology, Oxidative stress, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Superoxide Dismutase-1 - metabolism, Umbilical Veins - cytology, Umbilical Veins - enzymology