Details

Autor(en) / Beteiligte

• Alom, Nur-E
• Wu, Fan
• Li, Wei

Titel

One-Pot Strategy for Thiazoline Synthesis from Alkenes and Thioamides

Ist Teil von

• Organic letters, 2017-02, Vol.19 (4), p.930-933

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A convenient synthesis of a privileged pharmaceutical motif, thiazoline is accomplished. This reaction utilizes simple and readily available alkene and thioamide substrates in an intermolecular fashion via a simple one-pot procedure. A wide range of functional groups is tolerated, and the thiazoline product has been further utilized for the synthesis of the corresponding β-aminothiol and thiazole from routine hydrolysis and oxidation protocols.