Details

Autor(en) / Beteiligte

• Bystry, Vojtech
• Reigl, Tomas
• Krejci, Adam
• Demko, Martin
• Hanakova, Barbora
• Grioni, Andrea
• Knecht, Henrik
• Schlitt, Max
• Dreger, Peter
• Sellner, Leopold
• Herrmann, Dietrich
• Pingeon, Marine
• Boudjoghra, Myriam
• Rijntjes, Jos
• Pott, Christiane
• Langerak, Anton W
• Groenen, Patricia J T A
• Davi, Frederic
• Brüggemann, Monika
• Darzentas, Nikos
• Birol, Inanc

Titel

ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data

Ist Teil von

• Bioinformatics (Oxford, England), 2017-02, Vol.33 (3), p.435-437

Ort / Verlag

England

Erscheinungsjahr

2017

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations. ARResT/Interrogate is implemented primarily in R, and is freely available at http://bat.infspire.org/arrest/interrogate/ nikos.darzentas@gmail.com Supplementary data are available at Bioinformatics online.