Bulletin of experimental biology and medicine, 2016-12, Vol.162 (2), p.264-268
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Morphogenesis of Experimental Infection Caused by Plasmid Variants of Yersinia pseudotuberculosis
- Ist Teil von
- Bulletin of experimental biology and medicine, 2016-12, Vol.162 (2), p.264-268
- Ort / Verlag
- New York: Springer US
- Erscheinungsjahr
- 2016
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The dynamics of pathomorphological changes in response to infection with plasmid variants of Yersinia pseudotuberculosis was studied in experimental animals. Variability of cell injuries in pseudotuberculosis histopathology depended on the plasmid-associated virulence of the infection agent. Infection with highly virulent two-plasmid strain pYV48:pVM82 MDa and Y. pseudotuberculosis strain with low virulence with the only plasmid pVM82 MDa led to the development of cell destruction (necrosis and apoptosis) in the target organs. Apoptosis predominated in response to infection by plasmid variant pVM82 MDa with low virulence.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0007-4888eISSN: 1573-8221DOI: 10.1007/s10517-016-3591-zTitel-ID: cdi_proquest_miscellaneous_1863210430
- Format
- –
- Schlagworte
- Animals, Animals, Outbred Strains, Apoptosis, Biomedical and Life Sciences, Biomedicine, Cell Biology, Experimental infection, Genetic aspects, Health aspects, Hepatocytes - microbiology, Hepatocytes - pathology, Histochemistry, Humans, Infection, Infections, Injections, Intraperitoneal, Internal Medicine, Kupffer Cells - microbiology, Kupffer Cells - pathology, Laboratory Medicine, Liver - microbiology, Liver - pathology, Lung - microbiology, Lung - pathology, Lymph Nodes - microbiology, Lymph Nodes - pathology, Male, Mice, Morphogenesis, Necrosis - microbiology, Necrosis - pathology, Pathology, Phagocytes - microbiology, Phagocytes - pathology, Plasmids - chemistry, Plasmids - metabolism, Pseudotuberculosis, Species Specificity, Spleen - microbiology, Spleen - pathology, Virulence, Virulence (Microbiology), Yersinia pseudotuberculosis, Yersinia pseudotuberculosis - genetics, Yersinia pseudotuberculosis - growth & development, Yersinia pseudotuberculosis - pathogenicity, Yersinia pseudotuberculosis Infections - microbiology, Yersinia pseudotuberculosis Infections - pathology