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Lung cancer stem cells: The root of resistance
Cancer letters, 2016-03, Vol.372 (2), p.147-156
2016

Details

Autor(en) / Beteiligte
Titel
Lung cancer stem cells: The root of resistance
Ist Teil von
  • Cancer letters, 2016-03, Vol.372 (2), p.147-156
Ort / Verlag
Ireland: Elsevier Ireland Ltd
Erscheinungsjahr
2016
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
  • Highlights • Therapeutic resistance and tumor recurrence is common in lung cancer. • Cancer stem cells (CSCs) have the ability to self-renew and differentiate. • CSCs display robust intrinsic resistance to chemotherapy. • Targeting CSCs may enhance tumor response and prevent relapse in NSCLC patients. • Further studies are warranted in the targeting of resistant tumorigenic lung CSCs.
Sprache
Englisch
Identifikatoren
ISSN: 0304-3835
eISSN: 1872-7980
DOI: 10.1016/j.canlet.2016.01.012
Titel-ID: cdi_proquest_miscellaneous_1859483985
Format
–
Schlagworte
Animals, Antineoplastic Agents - therapeutic use, Biomarkers, Tumor - genetics, Biomarkers, Tumor - metabolism, Breast cancer, Cancer stem cells, Cancer therapies, Cell Differentiation - drug effects, Cell division, Cell Proliferation - drug effects, Chemotherapy, Clinical trials, Cytotoxicity, Drug Resistance, Neoplasm - genetics, Drugs, Hematology, Oncology and Palliative Medicine, Humans, Hypotheses, Lung cancer, Lung Neoplasms - drug therapy, Lung Neoplasms - genetics, Lung Neoplasms - metabolism, Lung Neoplasms - pathology, Markers, Medical prognosis, Metastasis, Molecular Targeted Therapy, Mortality, Neoplastic Stem Cells - drug effects, Neoplastic Stem Cells - metabolism, Neoplastic Stem Cells - pathology, Patients, Phenotype, Population, Resistance, Side-Population Cells - drug effects, Side-Population Cells - metabolism, Side-Population Cells - pathology, Signal Transduction - drug effects, Stem cells, Studies, Telomerase

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