Details

Autor(en) / Beteiligte

• Bakker, RC
• Veenstra, J
• Dingemans-Dumas, AM
• Wetsteyn, JCFM
• Kager, PA

Titel

Imported Dengue in The Netherlands

Ist Teil von

• Journal of travel medicine, 1996-12, Vol.3 (4), p.204-208

Ort / Verlag

England

Erscheinungsjahr

1996

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Background: The clinical manifestations of imported dengue in adult Western travelers were analyzed. Methods: The charts of all adult patients with dengue, who were seen in an academic hospital in The Netherlands from 1985 to 1994, were studied. Results: Dengue was confirmed in 34 patients by a fourfold rise in complement fixation antibody titer or presence of IgM. Twelve probable cases with a single high titer in the complement fixation test were found. Annual numbers have increased since 1989. Most cases were imported from Asia. Malaise (98%), fever (96%), headache (64%), chills (58%), muscle pain (53%) and arthralgia (44%) were the main symptoms. A noncharacteristic skin eruption was seen in 84%. Leukocytopenia and thrombocytopenia were found in 87% and 75%, respectively during the first week, and elevated serum aminotransferase activities were noted in 75%. Only two patients developed dengue hemorrhagic fever. Conclusions: Dengue in Western travelers is usually a relatively mild disease. Leukocytopenia, thrombocytopenia, and elevation of serum aminotransferase activities are common laboratory features.