Details

Autor(en) / Beteiligte

• Zao, Chih-Ling
• Tomanek, Lisa
• Cooke, Anthony
• Berger, Ron
• Yang, Lingyan
• Xie, Chen
• Chen, Si
• Shi, Changjun
• Rong, Rong

Titel

A novel simian retrovirus subtype discovered in cynomolgus monkeys (Macaca fascicularis)

Ist Teil von

• Journal of general virology, 2016-11, Vol.97 (11), p.3017-3023

Ort / Verlag

England

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• A new simian retrovirus (SRV) subtype was discovered in China and the USA from Cambodian-origin cynomolgus monkeys. Histopathological examination from necropsied animals showed multifocal lymphoplasmacystic and histocytic inflammation. The complete genome sequences demonstrated that the US virus isolates were nearly identical (99.91-99.93 %) and differed only slightly (99.13-99.16 % identical) from the China isolate. Phylogenetic analysis showed that the new virus isolates formed a distinct branch of SRV-1 through -7, and therefore were named this subtype, SRV-8. This SRV-8 variant was also phylogenetically and serologically more closely related to SRV-4 than any other SRV subtype.