Details

Autor(en) / Beteiligte

• Torrecillas, S.
• Mompel, D.
• Caballero, M.J.
• Montero, D.
• Merrifield, D.
• Rodiles, A.
• Robaina, L.
• Zamorano, M.J.
• Karalazos, V.
• Kaushik, S.
• Izquierdo, M.

Titel

Effect of fishmeal and fish oil replacement by vegetable meals and oils on gut health of European sea bass (Dicentrarchus labrax)

Ist Teil von

• Aquaculture, 2017-02, Vol.468, p.386-398

Ort / Verlag

Elsevier B.V

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The main objective of this study was to assess the effects of graded levels of replacement of fishmeal (FM) and fish oil (FO) by terrestrial meals (TM) and vegetable oils (VO) on gut health of European sea bass (Dicentrarchus labrax) based on gut morphology, gut-associated immune system (GALT) and gut microbiota composition. Reducing the dietary FM and FO levels down to 10 and 3%, respectively did not affect the growth of European sea bass. Increase in TM and VO markedly affected anterior and posterior gut morphology and fatty acid composition, which mirrored the dietary fatty acid profile. FO replacement by VO increased lipid deposition in anterior gut lamina propria, denoting an effect in lipid metabolism and lipoprotein synthesis. In posterior gut, FM replacements by TM induced an engrossment of the submucosa, an up-regulation of the proinflammatory cytokines IL-1β and TNFα genes, a relatively high mucus production and changes in mucosal microbiota profiles. Finally, supplementation of 0%FM-0%FO diets with LC-PUFA contributed to maintain gut homeostasis in terms of GALT response and microbiota profiles alterations. FM and FO appropriate dietary levels for European seabass •It is possible to reduce FM and FO down to 10 and 3% in diets for European sea bass juveniles without affecting fish growth.•A reduction of FM down to 5 or 0% significantly reduces growth.•FM replacements by alternative meals modify European sea bass posterior gut cytokine microenvironment.•FM replacements by alternative meals modulate of the mucosa microbial species populations.•FO replacement by VO increases lipid deposition in the anterior intestinal lamina propria.•Supplementation of 0%FM/0%FO diets with LC-PUFA contributed to maintain gut homeostasis in relation to GALT response and microbiota profiles.