Brain, behavior, and immunity, 2017-07, Vol.63, p.160-175
2017
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- Autor(en) / Beteiligte
- Titel
- Early-life stress lastingly alters the neuroinflammatory response to amyloid pathology in an Alzheimer’s disease mouse model
- Ist Teil von
- Brain, behavior, and immunity, 2017-07, Vol.63, p.160-175
- Ort / Verlag
- Netherlands: Elsevier Inc
- Erscheinungsjahr
- 2017
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Highlights • Aβ is differently altered depending on the age/neuropathology by early-life stress. • Neuroinflammation is affected through life by early-life stress in C57Bl/6 mice. • Neuroinflammatory response to Aβ is modulated by early-life stress in APP/PS1 mice. • Hippocampus is more affected by early-life stress compared to the entorhinal cortex.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0889-1591eISSN: 1090-2139DOI: 10.1016/j.bbi.2016.12.023Titel-ID: cdi_proquest_miscellaneous_1853746232
- Format
- –
- Schlagworte
- Allergy and Immunology, Alzheimer Disease - metabolism, Alzheimer Disease - pathology, Alzheimer’s disease, Amyloid, Amyloid - immunology, Amyloid - physiology, Amyloid beta-Peptides - metabolism, Amyloid beta-Protein Precursor - genetics, Amyloidosis - pathology, Animals, Disease Models, Animal, Disease Progression, Early life, Hippocampus, Hippocampus - metabolism, Humans, Inflammation, Interleukin-1beta - metabolism, Interleukin-6 - metabolism, Mice, Mice, Transgenic, Microglia, Microglia - metabolism, Neuroimmune, Neuroimmunomodulation - immunology, Plaque, Amyloid, Psychiatry, Stress, Stress, Psychological - genetics, Stress, Psychological - immunology