Neuroscience, 2017-02, Vol.343, p.250-259
2017
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Details
- Autor(en) / Beteiligte
- Titel
- Systemic blood pressure alters cortical blood flow and neurovascular coupling during nociceptive processing in the primary somatosensory cortex of the rat
- Ist Teil von
- Neuroscience, 2017-02, Vol.343, p.250-259
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2017
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Highlights • Blood pressure changes lead to inaccurate measures of CBF changes during nociception. • In turn, this leads to alteration of neurovascular coupling. • These effects vary depending on stimulus intensity and location (ipsilateral or contralateral). • This impacts on neuroimaging of nociceptive processes in anesthetized animals. • It remains to be determined how these findings apply to human.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-4522eISSN: 1873-7544DOI: 10.1016/j.neuroscience.2016.12.014Titel-ID: cdi_proquest_miscellaneous_1851302237
- Format
- –
- Schlagworte
- Anesthetics, Inhalation - pharmacology, Animals, blood pressure, Blood Pressure - physiology, cerebral blood flow, Cerebrovascular Circulation - physiology, Electric Stimulation, Forelimb - physiopathology, Isoflurane - pharmacology, local field potentials, Male, Neurology, neurovascular coupling, Neurovascular Coupling - physiology, nociception, Nociceptive Pain - physiopathology, pain, Pain Perception - physiology, Rats, Wistar, Somatosensory Cortex - physiopathology