Details

Autor(en) / Beteiligte

• Koehler, Philipp
• Hamprecht, Axel
• Bader, Oliver
• Bekeredjian-Ding, Isabelle
• Buchheidt, Dieter
• Doelken, Gottfried
• Elias, Johannes
• Haase, Gerhard
• Hahn-Ast, Corinna
• Karthaus, Meinolf
• Kekulé, Alexander
• Keller, Peter
• Kiehl, Michael
• Krause, Stefan W
• Krämer, Carolin
• Neumann, Silke
• Rohde, Holger
• La Rosée, Paul
• Ruhnke, Markus
• Schafhausen, Philippe
• Schalk, Enrico
• Schulz, Katrin
• Schwartz, Stefan
• Silling, Gerda
• Staib, Peter
• Ullmann, Andrew
• Vergoulidou, Maria
• Weber, Thomas
• Cornely, Oliver A
• Vehreschild, Maria J.G.T

Titel

Epidemiology of invasive aspergillosis and azole resistance in patients with acute leukaemia: the SEPIA Study

Ist Teil von

• International journal of antimicrobial agents, 2017-02, Vol.49 (2), p.218-223

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2017

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Highlights • Among 2440 AML patients, the incidence of invasive aspergillosis (IA) was 6.4%. • Among 627 ALL patients, the incidence of IA was 3.8%. • Mortality of IA at Day 84 was 33.8% ( n  = 49) and attributable mortality was 26.9% ( n  = 39). • Only two episodes of IA due to azole-resistant Aspergillus fumigatus were observed. • A change of antifungal treatment practices in Germany does not appear warranted.