Details

Autor(en) / Beteiligte

• Rosenberg, Elli, MD, PhD
• Dent, Peter B., MD
• Denburg, Judah A., MD

Titel

Primary Immune Deficiencies in the Adult: A Previously Underrecognized Common Condition

Ist Teil von

• The journal of allergy and clinical immunology in practice (Cambridge, MA), 2016-11, Vol.4 (6), p.1101-1107

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2016

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The large majority of classified primary immune deficiency (PID) diseases present in childhood. Yet, most patients with PID are adults, with a large proportion experiencing onset of symptoms beyond their childhood years. Most of these are diagnosed predominantly with antibody defects, but cellular and other disorders are increasingly being identified in older patients as well. Moreover, advances in clinical immunology are allowing pediatric patients, even those with severe disease, to reach adulthood. Because of differences in the physiology and pathophysiology of children and adults, the presentation, diagnosis, and management of a complex chronic disease could differ significantly between these patient populations and therefore require modifications in approach.