Brain, behavior, and immunity, 2016-11, Vol.58, p.261-271
2016
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- Autor(en) / Beteiligte
- Titel
- Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment
- Ist Teil von
- Brain, behavior, and immunity, 2016-11, Vol.58, p.261-271
- Ort / Verlag
- Netherlands: Elsevier Inc
- Erscheinungsjahr
- 2016
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Contradictory results concerning SSRI effects on inflammation were reported. • The effects of fluoxetine on inflammation are dependent on the environment. • In the enriched condition, fluoxetine is pro-inflammatory compared to vehicle. • In the stressful condition, fluoxetine is anti-inflammatory compared to vehicle.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0889-1591eISSN: 1090-2139DOI: 10.1016/j.bbi.2016.07.155Titel-ID: cdi_proquest_miscellaneous_1837290687
- Format
- –
- Schlagworte
- Allergy and Immunology, Animals, Antidepressant, Cytokines, Cytokines - metabolism, Depression, Encephalitis - metabolism, Environment, Fluoxetine - administration & dosage, Hippocampus - drug effects, Hippocampus - metabolism, Inflammation, Inflammation Mediators - metabolism, Major depression, Male, Mice, Inbred C57BL, Microglia, Microglia - drug effects, Microglia - physiology, Plasticity, Psychiatry, Serotonin, Serotonin Uptake Inhibitors - administration & dosage, SSRI, Stress, Psychological, Undirected susceptibility to change hypothesis