Advanced healthcare materials, 2016-08, Vol.5 (16), p.2013-2018
2016
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Details
- Autor(en) / Beteiligte
- Titel
- A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens
- Ist Teil von
- Advanced healthcare materials, 2016-08, Vol.5 (16), p.2013-2018
- Ort / Verlag
- Germany: Blackwell Publishing Ltd
- Erscheinungsjahr
- 2016
- Quelle
- Wiley Online Library Journals Frontfile Complete
- Beschreibungen/Notizen
- A peptide hydrogel with an antimicrobial activity is developed as a bandage contact lens. The antimicrobial activity is enhanced with the addition of the biomolecules penicillin G or poly‐ε‐lysine and is positive against Staphylococcus aureus and Escherichia coli. The lens is also noncytotoxic toward a human corneal epithelial cell line and as a consequence is of great potential as a drug‐eluting bandage lens replacing conventional corneal ulcer treatment.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2192-2640eISSN: 2192-2659DOI: 10.1002/adhm.201600258Titel-ID: cdi_proquest_miscellaneous_1835562563
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - chemistry, Anti-Bacterial Agents - pharmacology, Antiinfectives and antibacterials, antimicrobial, Antimicrobial agents, bandage lens, Biotechnology, Contact, Contact Lenses, cornea, Cornea - microbiology, drug delivery, Epithelial Cells - microbiology, Escherichia coli, Escherichia coli - growth & development, Humans, hydrogel, Hydrogels, Hydrogels - chemistry, Hydrogels - pharmacology, Lenses, Medical materials, Penicillin, Penicillin G - chemistry, Penicillin G - pharmacology, Peptides, Polylysine - chemistry, Polylysine - pharmacology, Staphylococcus aureus, Staphylococcus aureus - growth & development