Details

Autor(en) / Beteiligte

• Fukuzawa, Hiroaki
• Shiima, Yuko
• Mishima, Yasuhiko
• Sekine, Sachi
• Miura, Shizu
• Yabe, Kiyoaki
• Yamaki, Satoshi
• Morita, Keiichi
• Okata, Yuichi
• Hisamatsu, Chieko
• Nakao, Makoto
• Yokoi, Akiko
• Maeda, Kosaku
• Kosaka, Yoshiyuki

Titel

Predictive factor for intraoperative tumor rupture of Wilms tumor

Ist Teil von

• Pediatric surgery international, 2017-01, Vol.33 (1), p.91-95

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose For Wilms tumor, intraoperative tumor rupture with wide tumor spillage during surgical manipulation raises the classification to stage 3. Then, postoperative chemotherapy must be more intensive, and abdominal radiotherapy is added. Therefore, intraoperative tumor rupture should be avoided if possible. However, predictive factors for intraoperative tumor rupture have not been sufficiently described. Here we examined the risk factors for intraoperative tumor rupture. Methods Patients with Wilms tumor who underwent treatment according to the National Wilms Tumor Study or the Japanese Wilms Tumor Study protocol at our institution were reviewed retrospectively. Collected cases were categorized into two groups: the ruptured group and the non-ruptured group. Risk factors for intraoperative tumor rupture, including the ratio of the tumor area to the abdominal area in a preoperative single horizontal computed tomography slice ( T/A ratio), were investigated in both groups. Results The two groups were not different in age, body weight, tumor laterality, sex, or histological distribution. The T/A ratio in the ruptured group was significantly higher than that in the non-ruptured group. Receiver operating characteristic curve analysis identified a discriminative value for a T/A ratio >0.5. Conclusion The T/A ratio can be a predictive factor for intraoperative tumor rupture of Wilms tumor.