Details

Autor(en) / Beteiligte

• González-Mesa, Ana, PhD
• Paz Moreno-Arrones, Javier, MD
• Ferrari, Daniele, MD
• Teus, Miguel A., MD, PhD

Titel

Role of tear osmolarity in dry eye symptoms after cataract surgery

Ist Teil von

• American journal of ophthalmology, 2016-10, Vol.170, p.128-132

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Purpose To analyze changes in tear osmolarity and the Ocular Surface Disease Index (OSDI) in patients after cataract surgery. Design Prospective, observational cohort study. Methods Setting: Institutional. Patient Population: Fifty-two patients with a unilateral cataract (study eye) scheduled for surgery and good visual function in the fellow (control eye). Patients were excluded who were receiving chronic topical therapy, such as glaucoma medications, or had a history of previous ocular surgery. Intervention: Examinations were performed preoperatively and 1 and 3 months postoperatively. At each visit, complete anterior and posterior segment examinations were performed. Main Outcome Measures: Best-corrected and uncorrected visual acuities, tear osmolarity, and OSDI scores. Results The mean tear osmolarity values were, respectively, 305.63±15.07, 305.70±16.48, and 303.88±11.75 mOsmol/l at baseline and 1 and 3 months postoperatively ( P =0.067) compared with 309.74±15.92, 306.74±13.22, and 303.19±11.02 mOsmol/l at the same times in the unoperated control eyes ( P =0.064). Patients with normal osmolarity (<312 mOsmol/l) and hyperosmolarity values (≥312 mOsmol/l) had respective OSDI scores of 22.77±15.73 and 36.02±12.20 at baseline ( P =0.01), 12.44±12.44 and 14.45±13.45 at 1 month ( P =0.7), and 10.37±11.11 and 16.48±8.08 at 3 months postoperatively ( P =0.01). Conclusions We did not find differences in tear film osmolarity between the operated eyes, and the fellow unoperated control eyes at any time period during the study. Patients with tear osmolarity values of 312 mOsm/L or higher are more likely to have more ocular discomfort postoperatively. Ophthalmologists should consider evaluating tear osmolarity preoperatively, especially in highly demanding patients.