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Healthcare-associated Gram-negative Bloodstream Infections: Antibiotic Resistance and Predictors of Mortality
Ist Teil von
The Journal of hospital infection, 2016-12, Vol.94 (4), p.381-385
Ort / Verlag
England: Elsevier Ltd
Erscheinungsjahr
2016
Quelle
MEDLINE
Beschreibungen/Notizen
Abstract We described the prevalence of antibiotic resistance and predictors of fatality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause fatality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multivariate analysis showed that age >70 (OR:2, CI: 1.22-3.51), having a central venous catheter (OR:2.1, CI:1.09-4.07), ventilator associated pneumonia (OR:1.9, CI:1.1-3.16), carbapenem resistance (OR:1.8, CI:1.11-2.95), and APACHE II score (OR:1.1, CI:1.07-1.13) were significantly associated with fatality.