Details

Autor(en) / Beteiligte

• THIBAULT, Vincent
• AUBRON-OLIVIER, Camille
• AGUT, Henri
• KATLAMA, Christine

Titel

Primary infection with a lamivudine-resistant hepatitis B virus

Ist Teil von

• AIDS (London), 2002-01, Vol.16 (1), p.131-133

Ort / Verlag

Hagerstown, MD: Lippincott Williams & Wilkins

Erscheinungsjahr

2002

Quelle

MEDLINE

Beschreibungen/Notizen

• Hepatitis B virus (HBV) and HIV share common routes of transmission and are often found simultaneously in at-risk individuals. Antiretroviral therapies generally include lamivudine, which also possesses a strong activity against HBV replication. Unfortunately, prolonged treatment with this molecule is associated with the emergence of both HIV- and HBV-resistant strains. We now describe the case of an HIV-infected patient who, despite lamivudine treatment, developed an acute hepatitis B infection. This case raises several important questions about hepatitis B prevention and the treatment of lamivudine-resistant HBV.