Details

Autor(en) / Beteiligte

• Alonso López, Sonia
• Agudo Fernández, Sandra
• García Del Val, Antonia
• Martínez Abad, Mercedes
• López Hermosa Seseña, Paloma
• Izquierdo, María Jesús
• Núñez, Isabel
• Berbel León, Susana
• Visedo Campillo, Lourdes
• Guisado Pérez, Cristina
• Sánchez Lozano, Sandra
• Mariño Pfeiffer, Isabel
• García Bermúdez, Lourdes
• Sánchez Jiménez, Francisco Javier
• López Vega, Elena
• Zambrano Álvarez, Jesús
• Castro Pastor, M Luisa
• Montes Ramírez, Guadalupe
• Murillo, Cristina
• Villafranca Ortega, Noelia
• Ayuso Hernández, Isabel
• Espejo, María
• Lasala López, Pilar
• Rodríguez Caravaca, Gil
• Carrascosa Aguilar, Beatriz
• Gutiérrez García, María Luisa
• Fernández Rodríguez, Conrado

Titel

Hepatitis C seroprevalence in an at-risk population in the southwest Madrid region of Spain

Ist Teil von

• Gastroenterología y hepatología, 2016-12, Vol.39 (10), p.656-662

Ort / Verlag

Spain

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• The estimated seroprevalence of hepatitis C virus (HCV) in Spain is 1.7%, but is much higher in the at-risk population. The most efficient national screening strategy is unclear. To estimate the prevalence of HCV among the at-risk population seen in primary care (PC), and to determine their epidemiological profile. Cross-sectional descriptive prevalence study that included adult patients with risk factors for HCV infection seen in PC in the southwest Madrid region between 2010 and 2012. A total of 158 patients (men=51.3%), mean age 46 years (SD=16.6), were included. The most common risk factors were hypertransaminasaemia (44.3%) and major surgery (13.3%). Immigration, unsafe sexual practices, and tattoos or body piercing were more prevalent in patients younger than 45 years of age. Fifteen patients (9.5%) were positive for anti-HCV; 9 of these (5.7%) were HCV-ARN positive. Of the positive patients, 4 (44.4%) had significant fibrosis at diagnosis (F3-F4). Male patients had a higher rate of positive anti-HCV results (13.8 vs. 5.3%; P=.072), as did patients older than 45 years of age (12.8 vs. 6.3%; P=.167). Intravenous and intranasal drug use were associated with a higher rate of positive anti-HCV results (50 vs. 8.5%; P=.005 and 66.7 vs. 8.4%; P=.001, respectively). Patients with risk factors for HCV infection have high seroprevalence. Screening programmes must therefore be implemented to detect HCV infection in this population in PC.