Details

Autor(en) / Beteiligte

• Lee, Woohyung, MD
• Han, Ho-Seong, MD, PhD
• Yoon, Yoo-Seok, MD, PhD
• Cho, Jai Young, MD, PhD
• Choi, YoungRok, MD
• Shin, Hong Kyung, MD
• Jang, Jae Yool, MD
• Choi, Hanlim, MD
• Jang, Jae Seong, MD
• Kwon, Seong Uk, MD

Titel

Comparison of laparoscopic liver resection for hepatocellular carcinoma located in the posterosuperior segments or anterolateral segments: A case-matched analysis

Ist Teil von

• Surgery, 2016-11, Vol.160 (5), p.1219-1226

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Laparoscopic liver resection is an attractive option for treating liver tumors. Laparoscopic liver resection is more difficult for hepatocellular carcinomas located in the posterosuperior segments than for hepatocellular carcinomas in the anterolateral segments. We compared perioperative and long-term outcomes between laparoscopic liver resection for hepatocellular carcinomas located in the posterosuperior and anterolateral segments. Methods We retrospectively reviewed the clinical data for 230 patients who underwent laparoscopic liver resection for hepatocellular carcinomas between September 2003 and July 2014. Of these, 116 patients were selected by case-matched analysis using age, sex, tumor number and size, Child-Pugh class, and extent of liver resection. Patients were classified into 2 groups according to tumor location: the anterolateral group ( n  = 58) and the posterosuperior group ( n  = 58). Results Operation time (355 minutes vs 212 minutes, P  < .005), intraoperative blood loss (600 mL vs 410 mL, P  < .001), and hospital stay (8.5 days vs 7 days, P  = .040) were significantly greater in the posterosuperior group than in the anterolateral group. The open conversion (13.8% vs 10.3%, P  = .777), postoperative complication (17.2% vs 10.3%, P  = .420), 5-year overall survival (88.5% vs 85.7%, P  = .370), and 5-year, recurrence-free survival (47.6% vs 40.9%, P  = .678) rates were not significantly different between the posterosuperior and anterolateral groups. Conclusion Although laparoscopic liver resection is more difficult for hepatocellular carcinomas located in the posterosuperior segment, there were no differences in the short- and long-term outcomes between the posterosuperior and anterolateral groups. The perceived impact of tumor location on patient outcomes could be overcome by experience and technical improvements.