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Rotational atherectomy in very long lesions: Results for the ROTATE registry
Catheterization and cardiovascular interventions, 2016-11, Vol.88 (6), p.E164-E172
Iannaccone, Mario
Barbero, Umberto
D'ascenzo, Fabrizio
Latib, Azeem
Pennacchi, Mauro
Rossi, Marco Luciano
Ugo, Fabrizio
Meliga, Emanuele
Kawamoto, Hiroyoshi
Moretti, Claudio
Ielasi, Alfonso
Garbo, Roberto
Colombo, Antonio
Sardella, Gennaro
Boccuzzi, Giacomo G.
2016
Details
Autor(en) / Beteiligte
Iannaccone, Mario
Barbero, Umberto
D'ascenzo, Fabrizio
Latib, Azeem
Pennacchi, Mauro
Rossi, Marco Luciano
Ugo, Fabrizio
Meliga, Emanuele
Kawamoto, Hiroyoshi
Moretti, Claudio
Ielasi, Alfonso
Garbo, Roberto
Colombo, Antonio
Sardella, Gennaro
Boccuzzi, Giacomo G.
Titel
Rotational atherectomy in very long lesions: Results for the ROTATE registry
Ist Teil von
Catheterization and cardiovascular interventions, 2016-11, Vol.88 (6), p.E164-E172
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2016
Link zum Volltext
Quelle
Wiley Online Library (Online service)
Beschreibungen/Notizen
Background Rotational atherectomy (RA) is relatively contraindicated in patients with lesions ≥25 mm of length. Aim of this study was to evaluate RA safety and efficacy in this subset of patients with new technology and devices. Methods and Results From April 2002 to August 2013, the ROTATE registry included all consecutive patients undergoing RA in 8 centres. They were divided into shorter lesion group (SLG, lesions < 25 mm) and longer lesion group (LLG, lesions ≥ 25 mm). The angiographic success (AS) was the primary end point. Procedural complications (PC), a composite end point of procedural perforation, slow flow/no flow, and in‐hospital major acute cardiovascular events (MACE), were secondary end points, along with death, nonfatal MI, target lesion revascularization, and MACE during follow‐up. Sensitivity analysis was performed according to generation of DES. 1186 patients were included: 51.5% in SLG and 48.4% in LLG. Mean age was 70.4 ± 9.3 years, 64.5% were male. AS and PC did not differ between the two groups (93% vs 91%, p = 0.24 and 9.8 vs 9.4%, p = 0.84). During follow‐up (27.6 ± 22.9 months), MACE did not differ between the two groups (28% vs 29.1%, p = 0.95). At multivariate analysis chronic kidney disease, male gender increased risk of MACE (HR 1.94, IQR 1.29–2.0, p = 0.01, HR 0.52, IQR 0.34–0.79, p = 0.01) while second‐generation DES seemed protective (HR 0.53, IQR 0.31–0.88, p = 0.02). Data were confirmed at sensitivity analysis for second‐generation DES (759 pts, 63.9%). No differences were found in this subpopulation between the two groups in term of AS, PC, and long‐term MACE (93.6% vs 93.5%, p = 0.28, 11.9% vs 9.4%, p = 0.32 and 25.5% vs 23.9%, p = 0.72, respectively). Conclusions Treating coronary lesions ≥ 25 mm length with RA does not impact short‐ and long‐term outcome, in particular, in patients with second‐generation DES. © 2016 Wiley Periodicals, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 1522-1946
eISSN: 1522-726X
DOI: 10.1002/ccd.26548
Titel-ID: cdi_proquest_miscellaneous_1826670418
Format
–
Schlagworte
Aged
,
Atherectomy, Coronary - methods
,
calcific lesion
,
Coronary Angiography
,
Coronary Artery Disease - diagnosis
,
Coronary Artery Disease - surgery
,
Female
,
Follow-Up Studies
,
Humans
,
Male
,
Multivariate analysis
,
Percutaneous Coronary Intervention - methods
,
Registries
,
Retrospective Studies
,
rotablator
,
rotational atherectomy
,
second-generation DES
,
Severity of Illness Index
,
Stents
,
Time Factors
,
Treatment Outcome
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