Details

Autor(en) / Beteiligte

• DeGiorgio, Michael
• Huber, Christian D
• Hubisz, Melissa J
• Hellmann, Ines
• Nielsen, Rasmus

Titel

SweepFinder2: increased sensitivity, robustness and flexibility

Ist Teil von

• Bioinformatics, 2016-06, Vol.32 (12), p.1895-1897

Ort / Verlag

England

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• SweepFinder is a widely used program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the confounding effects of mutation rate variation and background selection. Moreover, SweepFinder2 has increased flexibility that enables the user to specify test sites, set the distance between test sites and utilize a recombination map. SweepFinder2 is a freely-available (www.personal.psu.edu/mxd60/sf2.html) software package that is written in C and can be run from a Unix command line. mxd60@psu.edu.