Details

Autor(en) / Beteiligte

• Al-Abed, Souhail R
• Virkutyte, Jurate
• Ortenzio, Jayna NR
• McCarrick, Robert M
• Degn, Laura L
• Zucker, Robert
• Coates, Najwa Haykal
• Childs, Kristin
• Ma, Hongbo
• Diamond, Steve
• Dreher, Kevin
• Boyes, William K

Titel

Environmental aging alters Al(OH) sub(3) coating of TiO sub(2) nanoparticles enhancing their photocatalytic and phototoxic activities

Ist Teil von

• Environmental science. Nano, 2016-06, Vol.3 (3), p.593-601

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• As a component of sunscreen formulations, TiO sub(2) engineered nanomaterials (ENM) are coated to prevent reactive oxygen species from causing damage to skin. We investigated the stability of an Al(OH) sub(3) coating by exposing 25 nm Al(OH) sub(3).TiO sub(2) ENM to simulated swimming pool water (SPW) for 45 minutes, 1, 3, 10, or 14 days. Electron microscopy and spectroscopy indicated that exposure to SPW caused a redistribution of the Al(OH) sub(3) coating allowing photocatalytic formation of hydroxyl radicals. Aged ENM showed significantly greater phototoxicity under UVA irradiation than un-aged ENM in a human-derived retinal pigment epithelium cell line (ARPE-19). Photocatalytic activity and phototoxicity of aged Al(OH) sub(3).TiO sub(2) was significantly less than that of the positive control-uncoated P25 TiO sub(2). In summary, the aging of Al(OH) sub(3).TiO sub(2) ENM in SPW redistributed the coating and reduced its protective properties, thereby increasing reactivity and potential phototoxicity.