Details

Autor(en) / Beteiligte

• Thummanapelli, Sravan K
• Hosseyni, Seyedmorteza
• Su, Yijin
• Akhmedov, Novruz G
• Shi, Xiaodong

Titel

Ligand-controlled gold-catalyzed cycloisomerization of 1,n-enyne esters toward synthesis of dihydronaphthalene

Ist Teil von

• Chemical communications (Cambridge, England), 2016-01, Vol.52 (49), p.7687-7690

Ort / Verlag

England

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We describe herein a gold-catalyzed rearrangement of propargyl esters followed by allene-ene cyclization to afford substituted bicyclic [4.4.0] dihydronaphthalene compounds. This method is also applied to vinylethers and vinylamines of 1,7-enyne esters to form dihydroquinoline and dihydrobenzopyran structures. The basis of this transformation is the ligand-controlled preferential activation of the alkene over the allene, affording the desired aromatic bicyclic structures in moderate to excellent yields.