Details

Autor(en) / Beteiligte

• Roberts, Calum T
• Owen, Louise S
• Manley, Brett J
• Frøisland, Dag H
• Donath, Susan M
• Dalziel, Kim M
• Pritchard, Margo A
• Cartwright, David W
• Collins, Clare L
• Malhotra, Atul
• Davis, Peter G

Titel

Nasal High-Flow Therapy for Primary Respiratory Support in Preterm Infants

Ist Teil von

• The New England journal of medicine, 2016-09, Vol.375 (12), p.1142-1151

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• This multicenter trial comparing nasal high-flow therapy with CPAP as primary support for preterm infants with respiratory distress showed a significantly higher treatment-failure rate with high-flow therapy. In 2014, there were more than 380,000 preterm births (i.e., births at a gestational age of <37 weeks) in the United States, accounting for approximately 10% of all births that year. 1 Preterm infants have a risk of the respiratory distress syndrome. The introduction of endotracheal ventilation has improved the survival rate among preterm infants but is associated with an increased risk of complications such as bronchopulmonary dysplasia. 2 Clinicians aim to use noninvasive respiratory support to minimize the risk of such complications. The most widely used noninvasive approach, nasal continuous positive airway pressure (CPAP), has been shown to be an effective . . .