Details

Autor(en) / Beteiligte

• Biondo, Sebastiano, M.D., Ph.D
• Trenti, Loris, M.D
• Elvira, Jordi, M.D
• Golda, Thomas, M.D., Ph.D
• Kreisler, Esther, M.D., Ph.D

Titel

Outcomes of colonic diverticulitis according to the reason of immunosuppression

Ist Teil von

• The American journal of surgery, 2016-09, Vol.212 (3), p.384-390

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Background The aims of this study were to analyze the relationship between the different causes of immunosuppression (IMS) and diverticulitis. Methods IMS patients admitted for colonic diverticulitis were included in the study. Patients were divided in 5 groups according to the reasons of IMS: group I, chronic corticosteroid therapy; group II, transplant patients; group III, malignant neoplasm disease; group IV, chronic renal failure; group V, others immunosuppressant treatment. Rate of emergency surgery, outcomes in terms of postoperative mortality, and recurrence rate after nonoperative management were analyzed according to the reason of IMS. Results Emergency surgery was performed in 76 patients (39.3%). It was needed more frequently in group I. Overall, postoperative mortality was of 31.6% and recurrence rate after successful nonoperative management occurred in 30 patients (27.8%). No differences were observed among the groups. Conclusions The rate of emergency surgery in IMS patients at the first episode of acute colonic diverticulitis is high. Elective surgery in IMS patients should be individually indicated according to persistence of symptoms or early recurrences.