Details

Autor(en) / Beteiligte

• Villanueva, V
• Garcés, M
• López-González, F.J
• Rodriguez-Osorio, X
• Toledo, M
• Salas-Puig, J
• González-Cuevas, M
• Campos, D
• Serratosa, J.M
• Giráldez, B. González
• Mauri, J.A
• Camacho, J.L
• Suller, A
• Carreño, M
• Gómez, J.B
• Montoya, J
• Uranga, J. Rodriguez
• Saiz-Diaz, R
• de la Aleja, J. González
• Castillo, A
• López-Trigo, J
• Poza, J.J
• Flores, J
• Querol, R
• Ojeda, J
• Giner, P
• Molins, A
• Esteve, P
• Baiges, J.J

Titel

Safety, efficacy and outcome-related factors of perampanel over 12 months in a real-world setting: The FYDATA study

Ist Teil von

• Epilepsy research, 2016-10, Vol.126, p.201-210

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Highlights • We report real-world data from 464 patients treated with perampanel over 1 year. • Efficacy and tolerability of perampanel were comparable with clinical trial data. • Patients ≥65 years, vascular aetiology or fewer prior AEDs had a superior response. • Patients with psychiatric comorbidities (hyperactivity and personality disorder) were more likely to experience psychiatric AEs. • Patients with slower titration schedules were less likely to experience an AE