Details

Autor(en) / Beteiligte

• Sakurai, Jun
• Matsui, Yusuke
• Hiraki, Takao
• Iguchi, Toshihiro
• Fujiwara, Hiroyasu
• Gobara, Hideo
• Mitsuhashi, Toshiharu
• Nagasaka, Takeshi
• Kanazawa, Susumu

Titel

Single Center Prospective Phase II Trial of CT-guided Radiofrequency Ablation for Pulmonary Metastases from Colorectal Cancer (SCIRO-1401)

Ist Teil von

• Acta medica Okayama, 2016-08, Vol.70 (4), p.317-321

Ort / Verlag

Japan

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• The present single center prospective phase II clinical trial is designed to evaluate the efficacy and safety of percutaneous radiofrequency (RF) ablation for colorectal lung metastases. Patients who have colorectal lung metastases without extrapulmonary metastases are included in this study. The primary endpoint is 3-year overall survival (OS) after RF ablation. The secondary endpoints are the prevalence of adverse events within 4 weeks, local tumor progression rate, 1- and 5-year OS, cause-specific survival, and relapse-free survival. The recruitment of patients commenced in July 2014, and the enrolment of 45 patients is intended over the 3 years of study period.