Details

Autor(en) / Beteiligte

• Zhang, Li-Hua
• Feng, Bao-Min
• Chen, Gang
• Li, Sheng-Ge
• Sun, Yi
• Wu, Hong-Hua
• Bai, Jiao
• Hua, Hui-Ming
• Wang, Hai-Feng
• Pei, Yue-Hu

Titel

Sporulaminals A and B: a pair of unusual epimeric spiroaminal derivatives from a marine-derived fungus Paraconiothyrium sporulosumYK-03

Ist Teil von

• RSC advances, 2016-04, Vol.6 (48), p.42361-42366

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Sporulaminals A (1) and B (2), a pair of unusual epimeric spiroaminal derivatives, bearing a 6/4/5/5 tetracyclic ring system derived from bergamotane sesquiterpenoid, were isolated from a marine-derived fungus Paraconiothyrium sporulosumYK-03. Their structures including the absolute configurations were elucidated by extensive NMR experiments, crystal X-ray diffraction and computational electronic circular dichroism (ECD) method. Furthermore, the epimerization induced by pH, temperature and H sub(2)O was revealed, together with the hypothetical biosynthetic pathway.