Details

Autor(en) / Beteiligte

• Green, Jeremy B A
• Sharpe, James

Titel

Positional information and reaction-diffusion: two big ideas in developmental biology combine

Ist Teil von

• Development (Cambridge), 2015-04, Vol.142 (7), p.1203-1211

Ort / Verlag

England

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• One of the most fundamental questions in biology is that of biological pattern: how do the structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in this area are those of Alan Turing's 'reaction-diffusion' and Lewis Wolpert's 'positional information'. Much has been written about these two concepts but some confusion still remains, in particular about the relationship between them. Here, we address this relationship and propose a scheme of three distinct ways in which these two ideas work together to shape biological form.