Details

Autor(en) / Beteiligte

• Davies, Jacob
• Svejstrup, Thomas D
• Fernandez Reina, Daniel
• Sheikh, Nadeem S
• Leonori, Daniele

Titel

Visible-Light-Mediated Synthesis of Amidyl Radicals: Transition-Metal-Free Hydroamination and N‑Arylation Reactions

Ist Teil von

• Journal of the American Chemical Society, 2016-07, Vol.138 (26), p.8092-8095

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The development of photoredox reactions of aryloxy-amides for the generation of amidyl radicals and their use in hydroamination–cyclization and N-arylation reactions is reported. Owing to the ease of single-electron-transfer reduction of the aryloxy-amides, the organic dye eosin Y was used as the photoredox catalyst, which results in fully transition-metal-free processes. These transformations exhibit a broad scope, are tolerant to several important functionalities, and have been used in the late-stage modification of complex and high-value N-containing molecules.