Details

Autor(en) / Beteiligte

• Hosseyni, Seyedmorteza
• Ding, Shengtao
• Su, Yijin
• Akhmedov, Novruz G
• Shi, Xiaodong

Titel

Triazole-gold promoted intermolecular propargyl alcohol addition to alkyne: the reaction cascade toward substituted allenes

Ist Teil von

• Chemical communications (Cambridge, England), 2016-01, Vol.52 (2), p.296-299

Ort / Verlag

England

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Gold-catalyzed intermolecular propargyl alcohol addition to alkyne was achieved. The reaction of propargyl alcohol with a typical gold catalyst gave the hydration product almost exclusively. The triazole gold catalyst (TA-Au) successfully prevented the hydration, giving the vinyl ether followed by a 3,3-rearrangement. Synthetically useful substituted allenes were formed with high efficiency, substrate tolerability and chemoselectivity. Also, more than 95% chirality transfer from propargyl alcohol to allene was obtained.