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Salvage surgery for patients with recurrent oral and oropharyngeal squamous cell carcinoma involving the carotid artery
Ist Teil von
Journal of oral and maxillofacial surgery, 2016-07, Vol.74 (7), p.1483-1493
Ort / Verlag
United States: Elsevier Inc
Erscheinungsjahr
2016
Quelle
MEDLINE
Beschreibungen/Notizen
Abstract Purpose Outcomes of salvage surgery and carotid artery (CA) management were evaluated in patients with oral and oropharyngeal cancer. Methods: Eighteen patients with recurrent oral and oropharyngeal squamous cell carcinoma involving the CA underwent salvage surgeries consisting of wide resection of the tumor, CA resection without and with reconstruction, and CA subadventitial dissection without and with encapsulation. Major tissue defects were reconstructed using a flap. Results: One patient showed postoperative transient hemiplegia, and wound dehiscence occurred at the recipient site in two patients. Two patients suffered carotid blowout. One patient who underwent CA resection and reconstruction suffered a carotid embolism. After 5–42 months of follow-up, 12 patients were disease-free, two remained ill, and four had died of local recurrence or distant metastases. Conclusions: Salvage surgery remains an effective treatment modality. CA sacrifice offers a viable treatment strategy. Major defects can be reconstructed with an trapezius flap.