Details

Autor(en) / Beteiligte

• Datla, Naresh V
• Konh, Bardia
• Koo, Joe J.Y
• Choi, Daniel J.W
• Yu, Yan
• Dicker, Adam P
• Podder, Tarun K
• Darvish, Kurosh
• Hutapea, Parsaoran

Titel

Polyacrylamide phantom for self-actuating needle–tissue interaction studies

Ist Teil von

• Medical engineering & physics, 2014-01, Vol.36 (1), p.140-145

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract This study presents a polyacrylamide gel as a phantom material for needle insertion studies specifically developed for self-actuating needles to enhance the precise placement of needles in prostate. Bending of these self-actuating needles within tissue is achieved by Nitinol actuators attached to the needle body; however these actuators usually involve heating that can thermally damage the tissue surrounding the needles. Therefore, to develop and access feasibility of these needles, a polyacrylamide gel has been developed that mimics the thermal damage and mechanical properties of prostate tissue. Mechanical properties of the polyacrylamide gel was controlled by varying the concentrations of acrylamide monomer and N , N -methylene-bisacrylamide (BIS) cross-linker, and thermal sensitivity was achieved by adding bovine serum albumin (BSA) protein. Two polyacrylamide gels with different concentrations were developed to mimic the elastic modulus of the tissue. The two phantoms showed different rupture toughness and different deflection of bevel-tip needle. To study the thermal damage, a Nitinol wire was embedded in the phantom and resistively heated. The measured opaque zone (0.40 mm) formed around the wire was close to the estimated damage zone (0.43 mm) determined using the cumulative equivalent minutes at 43 °C.