Details

Autor(en) / Beteiligte

• Mutsaerts, Meike A.Q
• van Oers, Anne M
• Groen, Henk
• Burggraaff, Jan M
• Kuchenbecker, Walter K.H
• Perquin, Denise A.M
• Koks, Carolien A.M
• van Golde, Ron
• Kaaijk, Eugenie M
• Schierbeek, Jaap M
• Oosterhuis, Gerrit J.E
• Broekmans, Frank J
• Bemelmans, Wanda J.E
• Lambalk, Cornelis B
• Verberg, Marieke F.G
• van der Veen, Fulco
• Klijn, Nicole F
• Mercelina, Patricia E.A.M
• van Kasteren, Yvonne M
• Nap, Annemiek W
• Brinkhuis, Egbert A
• Vogel, Niels E.A
• Mulder, Robert J.A.B
• Gondrie, Ed T.C.M
• de Bruin, Jan P
• Sikkema, J. Marko
• de Greef, Mathieu H.G
• ter Bogt, Nancy C.W
• Land, Jolande A
• Mol, Ben W.J
• Hoek, Annemieke

Titel

Randomized Trial of a Lifestyle Program in Obese Infertile Women

Ist Teil von

• The New England journal of medicine, 2016-05, Vol.374 (20), p.1942-1953

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• In this randomized trial, rates of vaginal birth of a healthy singleton at 2 years of follow-up were not higher among obese women who received a 6-month lifestyle intervention before infertility treatment than among those who received prompt infertility treatment. Obesity is a major public health problem. 1 In most developed countries, 14 to 20% of women of reproductive age are obese (body-mass index [BMI; the weight in kilograms divided by the square of the height in meters], ≥30), whereas in some countries, the prevalence of obesity is as high as 60%. 1 Obesity negatively affects female reproductive health because it is associated with increased risks of menstrual dysfunction, anovulation, and infertility. 2 – 4 Success rates with ovulation induction and assisted reproductive techniques are lower among obese infertile women than among normal-weight women. 5 , 6 The risks of miscarriage, 6 , 7 gestational diabetes, hypertensive disorders, . . .