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Carbon nanoparticle-guided central lymph node dissection in clinically node-negative patients with papillary thyroid carcinoma
Head & neck, 2016-06, Vol.38 (6), p.840-845
Zhu, Youzhi
Chen, Xiangjin
Zhang, Huihao
Chen, Ling
Zhou, Shujun
Wu, Kunlin
Wang, Zongcai
Kong, Lingjun
Zhuang, Hezhu
2016
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Zhu, Youzhi
Chen, Xiangjin
Zhang, Huihao
Chen, Ling
Zhou, Shujun
Wu, Kunlin
Wang, Zongcai
Kong, Lingjun
Zhuang, Hezhu
Titel
Carbon nanoparticle-guided central lymph node dissection in clinically node-negative patients with papillary thyroid carcinoma
Ist Teil von
Head & neck, 2016-06, Vol.38 (6), p.840-845
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2016
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
ABSTRACT Background Distinguishing the involved lymph nodes from other tissues during surgery is critical for lymph node dissection. The purpose of this study was to assess the feasibility by using carbon nanoparticles as guidance for lymph node dissection in patients with papillary thyroid carcinoma (PTC). Methods Eighty‐one patients were injected with carbon nanoparticles (carbon nanoparticle group), whereas the other 81 patients were not (control group). Routine pathological examination was performed. Results The lymph node dissection and metastatic lymph node dissection rates of the carbon nanoparticle group were significantly higher than that of the control group. In the carbon nanoparticle group, the number of mistakenly dissected parathyroid gland, the case number of postoperative hypocalcemia, the case number of postoperative hypoparathyroidism, and the recovery time from hypocalcemia were 4, 6, 8, and 2.33 ± 0.58 weeks, respectively, significantly less than 14, 17, 20, 3, and 3.8 ± 0.92 weeks in the control group (p < .05). Conclusion Carbon nanoparticles can be applied to more accurately guide the dissection of lymph nodes during thyroidectomy in patients with PTC. © 2015 Wiley Periodicals, Inc. Head Neck 38: 840–845, 2016
Sprache
Englisch
Identifikatoren
ISSN: 1043-3074
eISSN: 1097-0347
DOI: 10.1002/hed.24060
Titel-ID: cdi_proquest_miscellaneous_1789038381
Format
–
Schlagworte
Adult
,
Carbon
,
carbon nanoparticles
,
Carcinoma, Papillary - diagnostic imaging
,
Carcinoma, Papillary - pathology
,
Carcinoma, Papillary - surgery
,
clinically node-negative patients
,
Female
,
Humans
,
Intraoperative Period
,
lymph node dissection
,
Lymph Node Excision - methods
,
Lymph Nodes - diagnostic imaging
,
Lymphatic Metastasis - diagnostic imaging
,
Male
,
Middle Aged
,
Nanoparticles - adverse effects
,
papillary thyroid carcinoma
,
retrospective analysis
,
Retrospective Studies
,
Thyroid Cancer, Papillary
,
Thyroid Neoplasms - diagnostic imaging
,
Thyroid Neoplasms - pathology
,
Thyroid Neoplasms - surgery
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